12 January - 20 June 2016

Fat intake and prostate cancer

19 June 13

US scientists have studied dietary impact on men known to have prostate cancer, and concluded that among men with nonmetastatic prostate cancer, replacing carbohydrates and animal fat with vegetable fat may help reduce the risk of all-cause mortality. They argue that the potential benefit of vegetable fat for prostate cancer–specific outcomes merits further research. The researchers carried out a prospective study of 4577 men with nonmetastatic prostate cancer in the Health Professionals Follow-up Study (1986-2010) and monitored postdiagnostic intake of saturated, monounsaturated, polyunsaturated, trans, animal, and vegetable fat.  The same group of men was assessed for lethal prostate cancer and all-cause mortality. The researchers observed 315 events of lethal prostate cancer and 1064 deaths (median follow-up, 8.4 years).  Various secondary analyses were performed on the basic data to allow for/correct for other factors such as age at diagnosis, effects of alcohol and smoking, and the treatment regimes for the cancers, amongst others. Following this analysis the research team notes that replacing 10% of energy intake from carbohydrate with vegetable fat was associated with a lower risk of lethal prostate cancer and all-cause mortality. No other fats were associated directly with lethal prostate cancer. However, saturated and trans fats after diagnosis (replacing 5% and 1% of energy from carbohydrate, respectively) were associated with higher all-cause mortality.  These findings published in JAMA Internal Medicine support often-quoted general advice to minimise intake of animal fats, and to avoid trans and saturated fats where possible.

RSSL's Lipids Laboratory, part of the Investigative Analysis Team can determine the fatty acid profile of all dietary fats and oils including trans fats. For more information please contact Customer Services on Freephone 0800 243482 or email  enquiries@rssl.com

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