12 January - 20 June 2016

Vitamin C and E may weaken the positive effects of exercise

12 Feb 14

A small study by Paulsen et al. published in The Journal of Physiology suggests that vitamin C and E may weaken the positive effects of exercise. During endurance training the body adapts to generate more energy and improve muscular endurance. This adaptation is achieved by changing signalling in skeletal cell muscles and by increasing production of new muscle mitochondria. The latest research demonstrates that the vitamins C and E may disrupt cell signalling pathways and expression of certain genes. The study involved 54 young men and women who were randomly assigned to receive either a daily dose of 1000 mg vitamin C and 235 mg vitamin E or a placebo during 11 weeks of an endurance training programme. The participants primarily ran 3-4 times a week and took 500 mg vitamin C and 117 mg of vitamin E one to three hours before every training session and the same amount of vitamins in the hour after training. In order to investigate the effect of supplementation on the body’s adaptation, Paulsen et al. assessed the participants’ running performance (running until exhaustion), measured maximal oxygen uptake (VO2max) and performed biochemical and molecular analyses of blood and muscle to measure production of new muscle mitochondria. The tests were performed before and after the trial. VO2max and running performance improved to the same degree in the all groups. However, the mitochondria protein content increased only with training without the vitamin supplements. Similarly the levels of proteins that regulate cell signalling pathways and muscle cell processes were significantly higher in the placebo group. Paulsen et al. discussed that the effect of vitamin C and E may depend on the dose and the time of taking the supplements and they suggested caution when using high dosage of vitamin C and E during endurance training.

RSSL's Functional Ingredients Laboratory provides vitamin analysis in a wide range of matrices including drinks, fortified foods, pre-mixes and multi-vitamin tablets.  It provides a full vitamin and mineral analysis service to assist with labelling, due diligence, claim substantiation and stability. For more information please contact Customer Services on Freephone 0800 243482 or email enquiries@rssl.com

RSSL's Lipids Laboratory, part of the Investigative Analysis Team has considerable expertise in all aspects of fat analysis and fatty acid profiling and can analyse for both tocopherols and tocotrienols (forms of vitamin E).  To evaluate the healthy fats in your product please contact Customer Services on 0800 243482 or email enquiries@rssl.com

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