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Flaxseed mucilage shows promise for improvement in insulin sensitivity and gut microbiota

15 July 2015

A recent study published by Scandinavian researchers in the British Journal of Nutrition has investigated the effect of interventions with flaxseed mucilage or Lactobacillus paracasei F19 on gut microbiota and metabolic risk markers in obesity. 

The research participants consisted of 53 obese postmenopausal women who completed the study over a 6 week period. The participants had either a daily intake of flaxseed mucilage (10g), L.paracasei F19 or placebo. Changes in the gut microbiota were analysed through a quantitative metagenomics analysis of faecal DNA. Adjusted linear regression models were used to explore diet-induced changes in metabolic markers. 

The results of the study highlighted that daily intake of flaxseed mucilage over 6 weeks improved insulin sensitivity and modified the gut microbes in individuals with obesity. However, changes in the gut microbiota after the consumption of flaxseed mucilage was not a contributing factor to the beneficial effects of flaxseed mucilage on insulin sensitivity. Further to this, the researchers found a very limited effect of L.paracasei F19 on gut microbiota and metabolic markers which compared to the placebo group were non-significant.

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