12 January - 20 June 2016

Gut commensal E. coli proteins activate host satiety pathways following nutrient-induced bacterial growth

2 December 2015

A recent study conducted by INSERM Nutrition, Gut and Brain Laboratory in France has suggested a link between how full we feel during eating and the activity of our gut bacteria. While many studies have focused on the link between our gut bacterial biodiversity and nutrition, little is known about how our diet and the bacterial growth stimulated by this nutrition may affect our metabolism. This study demonstrates that bacterial growth depends on nutrient supply, for example, providing cultured bacteria with nutrients induces a long –lasting exponential and stationary growth phase. These stages stimulate production of different proteins. Breton et al. have shown that provision of regular nutrition stabilizes exponential growth of E. coli into the stationary phase around 20 minutes after nutrient supply. This is observed both in vitro and in vivo (using free feeding mice and rats). The change in growth phase is accompanied by bacterial proteome changes which activate the neurons within the brain that are associated with satiety.

share this article
RSSL endeavours to check the veracity of news stories cited in this free e-mail bulletin by referring to the primary source, but cannot be held responsible for inaccuracies in the articles so published. RSSL provides links to other World Wide Web sites as a convenience to users, but cannot be held responsible for the content or availability of these sites. This document may be copied and distributed provided the source is cited as RSSL's Food e-News and the information so distributed is not used for profit.

Previous editions

Load more editions

Make an Enquiry