Any chemical contaminant is a danger to patients and a problem for manufacturers.  Whether due to a accident, or deliberate act, whether from the external environment or from the packaging intended to protect the product, it is important that chemical contamination is detected, identified, explained and prevented.

Our expertise in contaminant analysis and identification in pharmaceutical products spans approximately 30 years. In that time, we have gained a reputation for being experts at identifying unknown peak, performing extractable and leachable studies, and investigating off-odours/off-colours and suspected contamination events. Our team's expert understanding of the variety of sampling, extraction and analytical methods available enables us to take the best sample possible, whatever the analyte, to provide you with a thorough and effective contaminant analysis. We undertake analytical services including chemical analysis as well as spectroscopy analysis (including FTIR spectroscopy, NMR and LC-MS).  In addition, we can undertake elemental determination using x-ray micro-fluorescence and energy dispersive x-ray analysis in the Scanning Electron Microscope as well as a semi-quantitative metals screen for ~70 elements using ICP-MS/OES.

We understand the business impact of chemical contamination on pharmaceutical products, and the importance of a rapid response. Work with us for chemical analysis, contaminant analysis and investigative consultancy and you gain an expert partner in resolving contamination issues, from initial identification of the contaminants in pharmaceuticals, to recognising its root cause (whether accidental or malicious), and taking appropriate corrective action to prevent a recurrent of a problem.

Contaminant analysis undertaken includes:

  • Heavy metals and elemental contamination
  • Cleaning agents including bleach and detergents
  • Hydrocarbons, including oils, petrol and diesel
  • Preservatives and colours
  • Cross contamination from packaging, production or storage

Techniques

FTIR (Fourier Transform InfraRed) Spectroscopy analysis 

GC-MS (Gas Chromatography-Mass Spectrometry) 

HPLC (High Performance Liquid Chromatography) & Preparative HPLC 

LC-MS (Liquid Chromatography-Mass Spectrometry) 

NMR (Nuclear Magnetic Resonance) Spectroscopy analysis 

UV-Visible Spectroscopy analysis 

Classical Wet Chemical Methods 

ICP-MS (Inductively Coupled Plasma Mass Spectrometry) 

ICP-OES (Inductively Coupled Plasma Optical Emission Spectroscopy)

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